Despite the difficulties in showing the effect most predators have on their prey, domestic cats are known to have serious impacts on small mammals and birds. Worldwide, cats may have been involved in the extinction of more bird species than any other cause, except habitat destruction. Cats are contributing to the endangerment of populations of birds such as Piping Plovers and Loggerhead Shrikes.

Not only do cats prey on many small mammals and birds, but they can out number and compete with native predators. Domestic cats eat many of the same animals that native predators do. When present in large numbers, cats can reduce the availability of prey for native predators, such as hawks and weasels . Free-ranging domestic cats may also transmit new diseases to wild animals.

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